She last acted with her ex-husband, Pawan Kalyan in his directorial, Johnny and then sticked to being behind the camera.
The actress after divorce with Pawan Kalyan, decided to move to Maharashtra and did produce & direct a Marathi film, Ishq vala Love. It failed at the box office.
She did few interviews, became journalist for Sakshi TV for few days and then went on to judge a reality show.
Many said she will enter Bigg Boss Season 3 as a contestant but she denied being part of the season and said she would considering hosting but not being a contestant.
Now, writer Sai Madhav Burra in an interview stated that Renu Desai could re-entry as an actress in Tiger Nageswara Rao, a famous thief and notorious criminal's biopic with Sai Sreenivas Bellamkonda as lead actor.
The actress did not confirm but the writer said that the team has approached and he is writing dialogues with cast in his mind as well.